How do you bind an Apex controller to a Visualforce page?

 In Visualforce, to reference an Apex method in the component markup, you must bind an Apex contoller to the Visualforce page. We do this by specifying  it as an attribute in the <apex:page> tag. 

Here's an example of how to do this:

<apex:page controller="MyController"> <!-- page content goes here --> </apex:page>

In this example, MyController is the name of the Apex controller class that you want to bind to the Visualforce page.

You can also specify multiple controllers by separating them with a comma, like this:

<apex:page controller="MyController1, MyController2"> <!-- page content goes here --> </apex:page>

It's important to note that the Apex controller class must be defined in your organization before you can bind it to a Visualforce page. 

public with sharing class MyController { // controller logic goes here }

Once you have defined your Apex controller class and specified it in the <apex:page> tag, you can use the controller's methods and variables in your Visualforce page to control the page's behavior and display dynamic content.